Article

The Effect of Repeat Length on Marcal1-Dependent Single-Strand Annealing in <i>Drosophila</i>

2022-09-25

Abstract excerpt

Proper repair of DNA double strand breaks (DSBs) is essential to maintenance of genomic stability and avoidance of genetic disease. Organisms have many ways of repairing DSBs, including use of homologous sequences through homology-directed repair (HDR). While HDR repair is often error-free, in single-strand annealing (SSA) homologous repeats flanking a DSB are annealed to one another, leading to deletion of one re...

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Literature Corpus work: 87713fc6-5202-59d4-acdb-2cc3853e49da
DOI: 10.1101/2022.09.24.509346

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