Article

Homology-directed repair involves multiple strand invasion cycles in fission yeast

2020-05-03

Abstract excerpt

Homology-directed repair of DNA double-strand breaks (DSBs) can be a highly faithful pathway. Non-crossover repair dominates in mitotically growing cells, likely through a preference for synthesis-dependent strand annealing (SDSA). While genetic studies highlight a key role for the RecQ helicase BLM/Rqh1 (in human and S. pombe cells, respectively) in promoting noncrossover repair, how homology-directed repair mec...

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Literature Corpus work: addd609f-8fb5-5bce-9943-65f7e6b99c76
DOI: 10.1101/2020.05.03.074468

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