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Article

Multiple pathways suppress telomere addition to DNA breaks in the Drosophila germline.

Genetics - 1 Jun 2012

Beaucher Michelle, Zheng Xiao-Feng, Amariei Flavia, Rong Yikang S

Abstract excerpt

Telomeres protect chromosome ends from being repaired as double-strand breaks (DSBs). Just as DSB repair is suppressed at telomeres, de novo telomere addition is suppressed at the site of DSBs. To identify factors responsible for this suppression, we developed an assay to monitor de novo telomere formation in Drosophila, an organism in which telomeres can be established on chromosome ends with essentially any...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22446318
DOI: 10.1534/genetics.112.138818
PMCID: PMC3374307

Genes

ATRIP
ATM
MDC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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