Mitotic Crossovers between Diverged Sequences Are Regulated by Mismatch Repair Proteins in <i>Saccharomyces cerevisiae</i>

Abstract excerpt

Mismatch repair systems correct replication- and recombination-associated mispaired bases and influence the stability of simple repeats. These systems thus serve multiple roles in maintaining genetic stability in eukaryotes, and human mismatch repair defects have been associated with hereditary predisposition to cancer. In prokaryotes, mismatch repair systems also have been shown to limit recombination between...