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Article

Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast.

Molecular cell - 17 Aug 2017

Guo Xiaoge, Hum Yee Fang, Lehner Kevin, Jinks-Robertson Sue

Abstract excerpt

Heteroduplex DNA (hetDNA) is a key molecular intermediate during the repair of mitotic double-strand breaks by homologous recombination, but its relationship to 5' end resection and/or 3' end extension is poorly understood. In the current study, we examined how perturbations in these processes affect the hetDNA profile associated with repair of a defined double-strand break (DSB) by the synthesis-dependent...

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Share to DNA Breaks, Double-Stranded
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28781235
DOI: 10.1016/j.molcel.2017.07.009
PMCID: PMC5584606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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