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Centenarians and Oldest Olds in Liguria – COOL: a multidisciplinary study to investigate the genetic determinants of cognitive well-being in Genoa, Italy. Rationale, study protocol and cohort profile

2026-05-28

Abstract excerpt

<h4>Objectives</h4> Despite the body of literature on genetic risk factors for dementia, little is known on protective genetic factors associated with favourable cognitive ageing in the oldest population. In Europe, Italy has a leading position with a swelling population of centenarians, and the urban area of Genoa in the Liguria region has one of the highest prevalence of centenarians. The COOL study is a not-fo...

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Literature Corpus work
85c512a7-da09-5a93-8428-6445b4361afd
DOI
10.64898/2026.05.20.26353506
Open publication

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Centenarians and Oldest Olds in Liguria – COOL: a multidisciplinary study to investigate the genetic determinants of cognitive well-being in Genoa, Italy. Rationale, study protocol and cohort profileDOI 10.64898/2026.05.20.26353506
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