Article

Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population

2020-10-14

Abstract excerpt

<h4>Importance</h4> Few studies have measured the effect of genetic factors on dementia and cognitive decline in a population of healthy older individuals followed prospectively. <h4>Objective</h4> To examine the effect of Apolipoprotein E ( APOE ) genotypes and a polygenic risk score (PRS) on incident dementia and cognitive decline in a longitudinal cohort of healthy older people. <h4>Design, Setting and Particip...

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Literature Corpus work: 4cda106c-9757-5406-9c0a-570eaf9a6d05
DOI: 10.1101/2020.10.11.20210963

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