Article

A non- <i>APOE</i> Polygenic score for Alzheimer’s disease and <i>APOE-ε4</i> have independent associations with dementia in the Health and Retirement Study

2020-02-11

Abstract excerpt

<h4>INTRODUCTION</h4> Alzheimer’s disease (AD) is a common and costly neurodegenerative disorder. A large proportion of risk is heritable and many genetic risk factors for AD have been identified. The cumulative genetic risk of known markers has not been benchmarked for dementia in a population-based sample. <h4>METHODS</h4> In the United States population-based Health and Retirement Study (HRS) (waves 1995-2014...

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Literature Corpus work: 922a6b6e-8cbd-55ad-afed-1f966c65ce8c
DOI: 10.1101/2020.02.10.20021667

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