Article

Exome-wide analysis reveals role of <i>LRP1</i> and additional novel loci in cognition

2022-10-14

Abstract excerpt

Cognitive functioning is heritable, with metabolic risk factors known to accelerate ageassociated cognitive decline. Identifying genetic underpinnings of cognition is thus crucial. Here, we undertake single-variant and gene-based association analyses upon six neurocognitive phenotypes across six cognition domains in whole-exome sequencing data from 157,160 individuals in the UK Biobank to expound the genetic archi...

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Literature Corpus work: 00cf44a6-33dd-5268-8963-a462bb063687
DOI: 10.1101/2022.10.12.511871

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