Article

Integrative pipeline for profiling DNA copy number and inferring tumor phylogeny

2017-09-28

Abstract excerpt

<h4>Summary</h4> Copy number variation is an important and abundant source of variation in the human genome, which has been associated with a number of diseases, especially cancer. Massively parallel next-generation sequencing allows copy number profiling with fine resolution. Such efforts, however, have met with mixed successes, with setbacks arising partly from the lack of reliable analytical methods to meet th...

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Literature Corpus work: 84d99422-abe7-59b3-847a-528c144a9d34
DOI: 10.1101/195230

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