Article

The Tangent copy-number inference pipeline for cancer genome analyses

2019-03-05

Abstract excerpt

<h4>Motivation</h4> Somatic copy-number alterations (SCNAs) play an important role in cancer development. Systematic noise in sequencing and array data present a significant challenge to the inference of SCNAs for cancer genome analyses. As part of The Cancer Genome Atlas (TCGA), the Broad Institute Genome Characterization Center developed the Tangent copy-number inference pipeline to generate copy-number profile...

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Literature Corpus work: c75c979b-c330-5657-bbee-2893cbbd5a75
DOI: 10.1101/566505

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