Article

Methods for Copy Number Aberration Detection from Single-cell DNA Sequencing Data

2019-07-09

Abstract excerpt

Single-cell DNA sequencing technologies are enabling the study of mutations and their evolutionary trajectories in cancer. Somatic copy number aberrations (CNAs) have been implicated in the development and progression of various types of cancer. A wide array of methods for CNA detection has been either developed specifically for or adapted to single-cell DNA sequencing data. Understanding the strengths and limitat...

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Literature Corpus work: 03fd2b69-7186-5cd3-8b01-ca59c2e12f96
DOI: 10.1101/696179

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