Article

SCONCE2: jointly inferring single cell copy number profiles and tumor evolutionary distances

2022-05-13

Abstract excerpt

Single cell whole genome tumor sequencing can yield novel insights into the evolutionary history of somatic copy number alterations. Existing single cell copy number calling methods do not explicitly model the shared evolutionary process of multiple cells, and generally analyze cells independently. Additionally, existing methods for estimating tumor cell phylogenies using copy number profiles are sensitive to prof...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2cbcc0b8-393d-5fe1-8ecd-231590974f18
DOI: 10.1101/2022.05.12.491742

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SCONCE2: jointly inferring single cell copy number profiles and tumor evolutionary distancesDOI 10.1101/2022.05.12.491742Read

SCONCE2: jointly inferring single cell copy number profiles and tumor evolutionary distances.Semantic proximity Read

Pharming: Joint Clonal Tree Reconstruction of Single-Nucleotide Variant and Copy Number Aberration Evolution from Single-Cell DNA Sequencing of Tumors.Semantic proximity Read

ConDoR: tumor phylogeny inference with a copy-number constrained mutation loss model.Semantic proximity Read

SCARLET: Single-cell tumor phylogeny inference with copy-number constrained mutation losses.Semantic proximity Read

Pharming: Joint Clonal Tree Reconstruction of SNV and CNA Evolution from Single-cell DNA Sequencing of TumorsSemantic proximity Read

SCONCE: a method for profiling copy number alterations in cancer evolution using single-cell whole genome sequencingSemantic proximity Read

COMPASS: joint copy number and mutation phylogeny reconstruction from amplicon single-cell sequencing data.Semantic proximity Read

Joint copy number and mutation phylogeny reconstruction from single-cell amplicon sequencing dataSemantic proximity Read

Phertilizer: Growing a clonal tree from ultra-low coverage single-cell DNA sequencing of tumorsSemantic proximity Read

ConDoR: Tumor phylogeny inference with a copy-number constrained mutation loss modelSemantic proximity Read

CONET: copy number event tree model of evolutionary tumor history for single-cell dataSemantic proximity Read

Integrative pipeline for profiling DNA copy number and inferring tumor phylogeny.Semantic proximity Read