Article

Basal forebrain parvalbumin neuron dysfunction links network oscillation deficits to hippocampal pathology in Alzheimer’s disease

2026-06-26

Abstract excerpt

<title>Abstract</title> <p>Background Basal forebrain (BF) degeneration is a key pathological feature of Alzheimer’s disease (AD) and is closely associated with cognitive decline. Although parvalbumin (PV)-expressing neurons are abundant in the BF and are important regulators of cortical network activity, their contribution to AD pathogenesis remains poorly understood. Methods To investigate the role of BF-PV n...

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Literature Corpus work: 83827b97-87d3-52b9-9c1e-24285ec66d48
DOI: 10.21203/rs.3.rs-10027900/v1

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