Article

Differential neural circuit vulnerability to β-amyloid and tau pathologies in novel Alzheimer’s disease mice

2023-04-12

Abstract excerpt

Alzheimer’s disease (AD) progresses with memory loss and neuropsychiatric symptoms associated with cell specific vulnerability in memory- and emotion-related neural circuits. Neuropathological and synaptic changes are key factors influencing the clinical progression to dementia, but how they cooperate to cause memory and emotional disturbances is largely unknown. Here, we employed pathological, behavioral, expansi...

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Literature Corpus work: f4b9550f-7558-5c38-bc21-85f3763ac9ed
DOI: 10.1101/2023.04.12.536603

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