Article

Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer’s disease

2023-06-26

Abstract excerpt

Alzheimer’s disease is a debilitating neurodegenerative disorder with no cure and few treatment options. In early stages of Alzheimer’s disease, impaired metabolism, and functional connectivity of the retrosplenial cortex strongly predict future cognitive impairments. Therefore, understanding Alzheimer’s disease-related deficits in the retrosplenial cortex is critical for understanding the origins of cognitive imp...

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Identifiers and source

Literature Corpus work: 481437db-449d-5850-8a4e-a5f1048f552a
DOI: 10.1101/2023.06.22.546142

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