Article

Ensemble-level organization of human kinetochores and evidence for distinct tension and attachment sensors

2019-06-28

Abstract excerpt

<h4>Summary</h4> Kinetochores are multi-protein machines that form dynamic attachments to microtubules and generate the forces for chromosome segregation. High-fidelity is ensured because kinetochores can monitor attachment status and tension, using this information to activate checkpoints and error correction mechanisms. To explore how kinetochores achieve this we used two and three colour subpixel fluorescence...

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Literature Corpus work: 833ef1e6-34f0-5de8-bb61-fcd29db6dccd
DOI: 10.1101/685248

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