Article

Bayesian data driven modelling of kinetochore dynamics: space-time organisation of the human metaphase plate

2025-01-22

Abstract excerpt

<h4>ABSTRACT</h4> Mitosis is a complex self-organising process that achieves high fidelity separation of duplicated chromosomes into two daughter cells through capture and alignment of chromosomes to the spindle mid-plane. Chromosome movements are driven by kinetochores, multi-protein machines that attach chromosomes to microtubules (MTs), both controlling and generating directional forces. Using lattice light sh...

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Literature Corpus work: a17b8228-c5a9-52b1-8aec-db00d040fc5d
DOI: 10.1101/2025.01.22.634311

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