Article

Tau Clearance Reverses Neuronal Dysfunction in Both Young and Aged <i>C. elegans</i>

2025-06-25

Abstract excerpt

Alzheimer’s Disease (AD) is an age-related dementia and presents a growing medical and economic burden as the average human lifespan continues to rise. AD is classically diagnosed via the accumulation and aggregation of two major proteins: amyloid-β and tau. To date, potential and FDA-approved therapies designed to clear these aggregates at best delay rather than prevent disease, indicating that the root cause of...

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Identifiers and source

Literature Corpus work: 82890505-cb2b-5a17-a68d-a132488789d4
DOI: 10.1101/2025.06.23.661052

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