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Studying the mechanisms of neurodegeneration: C. elegans advantages and opportunities

26 Mar 2025

Abstract excerpt

Caenorhabditis elegans has been widely used as a model organism in neurodevelopment for several decades due to its simplicity, rapid growth, short life cycle, transparency, and rather simple genetics. It has been useful in modeling neurodegenerative diseases by the heterologous expression of the major proteins that form neurodegenerative-linked aggregates such as amyloid- β peptide, tau protein, and α -synuclein,...

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PMID: 40207239
DOI: 10.3389/fncel.2025.1559151

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