Article

PCNA Modifications for Regulation of Post-Replication Repair Pathways

2008-07-01

Abstract excerpt

Stalled DNA replication forks activate specific DNA repair mechanism called post-replication repair (PRR) pathways that simply bypass DNA damage. The bypassing of DNA damage by PRR prevents prolonged stalling of DNA replication that could result in double strand breaks (DSBs). Proliferating cell nuclear antigen (PCNA) functions to initiate and choose different bypassing pathways of PRR. In yeast, DNA replication f...

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Literature Corpus work: 81e4e49c-cc02-5006-9ac7-3b94fa17a802
DOI: 10.1016/s1016-8478(23)13956-2

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