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The variation and evolution of complete human centromeres

2023-05-31

Abstract excerpt

<h4>ABSTRACT</h4> We completely sequenced and assembled all centromeres from a second human genome and used two reference sets to benchmark genetic, epigenetic, and evolutionary variation within centromeres from a diversity panel of humans and apes. We find that centromere single-nucleotide variation can increase by up to 4.1-fold relative to other genomic regions, with the caveat that up to 45.8% of centromeric...

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Literature Corpus work
8b9968a2-878c-5737-a533-c8322c503d14
DOI
10.1101/2023.05.30.542849
Open publication

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The variation and evolution of complete human centromeresDOI 10.1101/2023.05.30.542849
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