Article
Characterization of Human Ectocentromeric Sites
2026-06-01
Abstract excerpt
Centromeres are composed of DNA repeats within chromosomes’ primary constriction. CENP-B is the only centromeric protein known to bind a specific motif, the CENP-B box, promoting kinetochore stability. We recently uncovered degenerate CENP-B binding motifs outside centromeres, whose position and orientation defines chromosome specific banding patterns. Here, we leveraged telomere-to-telomere assemblies to map cons...
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Identifiers and source
- Literature Corpus work
- 3414ae9b-8aa0-529e-8478-13d6b0c5d3ef
- DOI
- 10.64898/2026.05.28.728588