Article
Non-B-form DNA structures mark centromeres
2017-10-25
Abstract excerpt
Animal and plant centromeres are embedded in repetitive “satellite” DNA, but are thought to be epigenetically specified. To define genetic characteristics of centromeres, we surveyed satellite DNA from diverse eukaryotes and identified variation in <10-bp dyad symmetries predicted to adopt non-B-form conformations. Organisms lacking centromeric dyad symmetries had binding sites for sequence-specific DNA binding pr...
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Identifiers and source
- Literature Corpus work
- 15ba6ae1-9f41-513e-a21d-337d256dd325
- DOI
- 10.1101/209023