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A Game of Thrones at Human Centromeres I. Multifarious structure necessitates a new molecular/evolutionary model

2019-08-10

Abstract excerpt

Human centromeres form over arrays of tandemly repeated DNA that are exceptionally complex (repeats of repeats) and long (spanning up to 8 Mbp). They also have an exceptionally rapid rate of evolution. The generally accepted model for the expansion/contraction, homogenization and evolution of human centromeric repeat arrays is a generic model for the evolution of satellite DNA that is based on unequal crossing ove...

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Literature Corpus work
ccc3a59e-a8c3-5cf2-be60-400f5447ebff
DOI
10.1101/731430
Open publication

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A Game of Thrones at Human Centromeres I. Multifarious structure necessitates a new molecular/evolutionary modelDOI 10.1101/731430
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