Article

<i>LRRK2</i> coding variants and the risk of Parkinson’s disease

2021-04-23

Abstract excerpt

<h4>Background</h4> The leucine-rich repeat kinase 2 ( LRRK2 ) gene harbors both rare highly damaging missense variants (e.g. p.G2019S) and common non-coding variants (e.g. rs76904798) with lower effect sizes that are associated with Parkinson’s disease risk. <h4>Objectives</h4> This study aimed to investigate in a large meta-analysis whether the LRRK2 GWAS signal represented by rs76904798 is independently associa...

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Literature Corpus work: 7b8c23ff-7c49-5b9d-be49-19542c228432
DOI: 10.1101/2021.04.22.21255928

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