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Article

Parkinson's disease and low frequency alleles found together throughout LRRK2.

Annals of human genetics - 1 Jul 2009

Paisán-Ruiz Coro, Washecka Nicole, Nath Priti, Singleton Andrew B, Corder Elizabeth H

Abstract excerpt

Mutations within LRRK2, most notably p.G2019S, cause Parkinson's disease (PD) in rare monogenic families, and sporadic occurrences in diverse populations. We investigated variation throughout LRRK2 (84 SNPs; genotype or diplotype found for 49 LD blocks) for 275 cases (European ancestry, onset at age 60 or older) and 275 neurologically healthy control subjects (NINDS Neurogenetics Repository). Three...

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Identifiers

PMID: 19489756
DOI: 10.1111/j.1469-1809.2009.00524.x
PMCID: PMC5217459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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