Article
Parkinson's disease and low frequency alleles found together throughout LRRK2.
Annals of human genetics - 1 Jul 2009
Paisán-Ruiz Coro, Washecka Nicole, Nath Priti, Singleton Andrew B, Corder Elizabeth H
Abstract excerpt
Mutations within LRRK2, most notably p.G2019S, cause Parkinson's disease (PD) in rare monogenic families, and sporadic occurrences in diverse populations. We investigated variation throughout LRRK2 (84 SNPs; genotype or diplotype found for 49 LD blocks) for 275 cases (European ancestry, onset at...
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