Article

Genetic Analysis and Natural History of Parkinson’s Disease Due to the LRRK2 G2019S Variant

2023-10-26

Abstract excerpt

The LRRK2 G2019S variant is the most common cause of monogenic Parkinson’s Disease (PD); however, questions remain regarding the penetrance, clinical phenotype, and natural history of carriers. We performed a 3.5 year prospective longitudinal online study in a large number of 1,286 genotyped LRRK2 G2019S carriers and 109,154 controls, with and without Parkinson’s disease (PD) recruited from the 23andMe Research Co...

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Literature Corpus work: a33a6dfb-d010-5365-9f13-da0a62b4c4a9
DOI: 10.1101/2023.10.26.23297636

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