Article

MDSGene update and expansion: Clinical and genetic spectrum of<i>LRRK2</i>variants in Parkinson’s disease

2024-12-10

Abstract excerpt

<h4>ABSTRACT</h4> Pathogenic variants in the LRRK2 gene are one of the most commonly identifiable monogenic causes of Parkinsońs disease (PD, PARK-LRRK2). This systematic MDSGene literature review comprehensively summarizes published demographic, clinical, and genetic findings related to potentially pathogenic LRRK2 variants ( https://www.mdsgene.org/ ). Recent insights on LRRK2’s kinase activity have been incorpo...

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Literature Corpus work: 8ef9e592-0530-5c88-adb0-3bf41834943f
DOI: 10.1101/2024.12.10.24318787

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