Article

High-throughput characterization of transcription factors that modulate UV damage formation and repair at single-nucleotide resolution

2025-12-10

Abstract excerpt

<title>Abstract</title> <p>Genomic studies have revealed elevated damage and mutation rates in active transcription factor (TF) binding sites in UV-linked cancers. Previous investigations into the relationship between TF activity and UV DNA damage have primarily focused on select TFs or been done in aggregate across large cohorts of TFs at kilobase resolution. While collectively, there is evidence that TFs contri...

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Literature Corpus work: 7b06fc06-0db9-5d66-92df-089e58f5a7fc
DOI: 10.21203/rs.3.rs-8197218/v1

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