Article

Nucleotide excision repair hotspots and coldspots of UV-induced DNA damage in the human genome

2020-04-18

Abstract excerpt

<h4>ABSTRACT</h4> We recently developed high-throughput sequencing approaches, eXcision Repair sequencing (XR-seq) and Damage-seq, to generate genome-wide mapping of DNA excision repair and damage formation, respectively, with single-nucleotide resolution. Here, we used time-course XR-seq data to profile UV-induced excision repair dynamics, paired with Damage-seq data to quantify the overall induced DNA damage. W...

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Literature Corpus work: bbfeb17e-86d8-5c03-916b-1f3b37f42241
DOI: 10.1101/2020.04.16.045369

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