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Article

Genomic sites hypersensitive to ultraviolet radiation.

Proceedings of the National Academy of Sciences of the United States of America - 26 Nov 2019

Premi Sanjay, Han Lynn, Mehta Sameet, Knight James, Zhao Dejian, Palmatier Meg A, Kornacker Karl, Brash Douglas E

Abstract excerpt

If the genome contains outlier sequences extraordinarily sensitive to environmental agents, these would be sentinels for monitoring personal carcinogen exposure and might drive direct changes in cell physiology rather than acting through rare mutations. New methods, adductSeq and freqSeq, provided statistical resolution to quantify rare lesions at single-base resolution across the genome. Primary human...

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Identifiers

PMID: 31723047
DOI: 10.1073/pnas.1907860116
PMCID: PMC6883822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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