Article

Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light

2019-05-17

Abstract excerpt

<h4>ABSTRACT</h4> Mutational signatures can reveal properties of underlying mutational processes and are important when assessing signals of selection in cancer. Here we describe the sequence characteristics of mutations induced by ultraviolet (UV) light, a major mutagen in several human cancers, in terms of extended (longer than trinucleotide) patterns as well as variability of the signature across chromatin sta...

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Literature Corpus work: 59d3a0a6-fff5-5c7e-93c0-7f494e0f7af2
DOI: 10.1101/640722

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