Article

Mosaic patterns of selection in genomic regions associated with diverse human traits

2022-05-08

Abstract excerpt

Natural selection shapes the genetic architecture of many human traits. However, the prevalence of different modes of selection on genomic regions associated with variation in traits remains poorly understood. To address this, we developed an efficient computational framework to calculate enrichment of different evolutionary measures among regions associated with complex traits. We applied the framework to summary...

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Literature Corpus work: 79897e04-8f62-5b5e-981c-dcb818cef7ae
DOI: 10.1101/2022.05.08.491080

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