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Genetic association data are broadly consistent with stabilizing selection shaping human common diseases and traits

2024-06-23

Abstract excerpt

<h4>Results: </h4> from genome-wide association studies (GWAS) enable inferences about the balance of evolutionary forces maintaining genetic variation underlying common diseases and other genetically complex traits. Natural selection is a major force shaping variation, and understanding it is necessary to explain the genetic architecture and prevalence of heritable diseases. Here, we analyze data for 27 traits, i...

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Identifiers and source

Literature Corpus work
6e8c1a0d-739a-5436-b01e-93bfd6cd8c84
DOI
10.1101/2024.06.19.599789
Open publication

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Genetic association data are broadly consistent with stabilizing selection shaping human common diseases and traitsDOI 10.1101/2024.06.19.599789
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