Article

Gene drive-based population suppression in the malaria vector <i>Anopheles stephensi</i>

2024-05-24

Abstract excerpt

Gene drives are alleles that can bias the inheritance of specific traits in target populations for the purpose of modification or suppression. Here, we constructed a homing suppression drive in the major urban malaria vector Anopheles stephensi targeting the female-specific exon of doublesex , incorporating two gRNAs and a nanos- Cas9 promoter to reduce functional resistance and improve female heterozygote fitn...

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Identifiers and source

Literature Corpus work: e2e6af8a-b06c-55ab-8267-7e91587dd776
DOI: 10.1101/2024.05.24.595689

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