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Article

Somatic mutation detection efficiency in EGFR: a comparison between High Resolution Melting Analysis and Sanger Sequencing

2020-09-16

Abstract excerpt

<title>Abstract</title> <p>Background : High resolution melting curve analysis is a cost-effective rapid screening method for detection of somatic gene mutation. The performance characteristics of this technique has been explored previously, however, analytical parameters such as limit of detection of mutant allele fraction and total concentration of DNA, have not been addressed. The current study focuses on comp...

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Literature Corpus work
782f4aa4-ea57-5880-b98e-3e38a0c01dca
DOI
10.21203/rs.3.rs-25257/v5
Open publication

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Somatic mutation detection efficiency in EGFR: a comparison between High Resolution Melting Analysis and Sanger SequencingDOI 10.21203/rs.3.rs-25257/v5
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