Article
[High-resolution melting analysis for the detection of EGFR mutations in circulating DNA of lung cancer patients].
Zhonghua yi xue za zhi - 15 Mar 2011
Zhao Jin, Peng Qun-xin, Yang Bing-hua, Lu Da-ru
Abstract excerpt
OBJECTIVE: To discuss the practicability of detecting epidermal growth factor receptor (EGFR) mutations in plasma circulating DNA of lung cancer patients by high-resolution melting (HRM). METHODS: The sensitivity of HRM was analyzed by the detection of samples containing different proportions of EGFR-mutated plasmids. The mutations in exons 19 and 21 of EGFR were detected by HRM in 96 lung cancer patients from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
