Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of EGFR and KRAS mutations on trans-thoracic needle aspiration of lung nodules by high resolution melting analysis.

Journal of clinical pathology - 1 Dec 2009

Fassina A, Gazziero A, Zardo D, Corradin M, Aldighieri E, Rossi G P

Abstract excerpt

BACKGROUND: EGFR and KRAS are the target genes for tumour response to epidermal growth factor receptor (EGFR) inhibitors. AIMS: To investigate EGFR and KRAS mutational status with high resolution melting (HRM) analysis applied to cytological material obtained from trans-thoracic needle aspiration...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy, Fine-Needle
Share to DNA, Neoplasm
Share to Neoplasm Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Staging

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Share to Transition Temperature

Source

Identifiers

PMID: 19640859
DOI: 10.1136/jcp.2009.067587

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19640859-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of EGFR and KRAS mutations on trans-thoracic needle aspiration of lung nodules by high resolution melting analysis.PMID 19640859Read ↗

Detection of EGFR mutations in patients with non-small cell lung cancer by high resolution melting. Comparison with other methods.Semantic proximity Read ↗

High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies.Semantic proximity Read ↗

A high-resolution melting protocol for rapid and accurate differential diagnosis of thyroid nodules.Semantic proximity Read ↗

Detection of epidermal growth factor receptor gene mutations in cytology specimens from patients with non-small cell lung cancer utilising high-resolution melting amplicon analysis.Semantic proximity Read ↗

Direct serum and tissue assay for EGFR mutation in non-small cell lung cancer by high-resolution melting analysis.Semantic proximity Read ↗

Detection of EGFR mutation in supernatant, cell pellets of pleural effusion and tumor tissues from non-small cell lung cancer patients by high resolution melting analysis and sequencing.Semantic proximity Read ↗

High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer.Semantic proximity Read ↗

Rapid and efficient detection of EGFR mutations in problematic cytologic specimens by high-resolution melting analysis.Semantic proximity Read ↗

High resolution melting analysis for epidermal growth factor receptor mutations in formalin-fixed paraffin-embedded tissue and plasma free DNA from non-small cell lung cancer patients.Semantic proximity Read ↗

Diagnostic accuracy of high resolution melting analysis for detection of KRAS mutations: a systematic review and meta-analysis.Semantic proximity Read ↗

Prospective study of the accuracy of EGFR mutational analysis by high-resolution melting analysis in small samples obtained from patients with non-small cell lung cancer.Semantic proximity Read ↗

A panel of high resolution melting (HRM) technology-based assays with direct sequencing possibility for effective mutation screening of EGFR and K-ras genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.