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Article

Rapid and efficient detection of EGFR mutations in problematic cytologic specimens by high-resolution melting analysis.

Molecular diagnosis & therapy - 1 Feb 2011

Hlinkova Katarina, Babál Pavel, Berzinec Peter, Majer Ivan, Ilencikova Denisa

Abstract excerpt

BACKGROUND AND OBJECTIVE: Chemotherapy for advanced non-small-cell lung cancer (NSCLC) remains marginally effective, with a 5-year overall survival rate of approximately 5%. Recently, the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib was approved in Slovakia for the treatment of metastatic NSCLC. Gefitinib is a selective EGFR inhibitor that binds to the adenosine triphosphate binding...

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PMID: 21469767
DOI: 10.1007/BF03257190

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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