Article

Alzheimer’s Disease and circadian disruption sex-specifically contribute to a loss of bone maintenance in APP/PS1 model mice

2026-05-05

Abstract excerpt

<h4>ABSTRACT</h4> Alzheimer’s Disease and Related Dementias (ADRDs) are linked to reduced bone integrity and increased fracture risk, but the mechanisms that underlie this risk remain poorly defined. Current research suggests that environmental factors, such as diet, sleep, and light exposure can modulate the brain-bone axis, increasing susceptibility to bone loss and fractures. Circadian disruption (CD) associat...

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Literature Corpus work: 77a23abd-63aa-5891-9ef5-b0fe2cc7f5e2
DOI: 10.64898/2026.05.01.722089

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