Article

The circadian clock regulates scavenging of fluid-borne substrates by brain border-associated macrophages

2025-12-11

Abstract excerpt

<h4>SUMMARY</h4> Circadian disruptions perturb the brain and immune system and increase the risk of developing Alzheimer’s Disease (AD), yet whether this involves dysregulation of brain immunity remains less clear. Here, we perform single-cell RNA sequencing of the brain immune compartment around the day-night cycle and identify brain border-associated macrophages (BAMs) as highly rhythmic cells. During the rest...

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Identifiers and source

Literature Corpus work: 1e029497-a5fb-5d7c-a78e-fe422726f907
DOI: 10.64898/2025.12.08.693074

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