Article

Dim light at night impacts circadian rhythms and Alzheimer’s disease-like neuroinflammation and neuropathology in humanized APP SAA knock-in mice

2025-10-03

Abstract excerpt

Artificial light at night (light pollution) is widespread but understudied in the context of Alzheimer’s disease (AD). Sleep and circadian disruption have been linked to amyloid-β (Aβ) accumulation and neuroinflammation, but whether dim light at night (dLAN) modifies these processes remains unclear. We tested whether chronic dLAN exposure (8 lux during the dark phase, 8 weeks) alters circadian rhythms, amyloid pat...

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Literature Corpus work: 8b074206-de07-5772-82b2-fb02b90740eb
DOI: 10.1101/2025.10.02.680043

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Dim light at night impacts circadian rhythms and Alzheimer’s disease-like neuroinflammation and neuropathology in humanized APP SAA knock-in miceDOI 10.1101/2025.10.02.680043Read

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