Article

Circadian disruption through light-dark cycle alteration induced Alzheimer's disease-like pathology in mice

2025-06-10

Abstract excerpt

<title>Abstract</title> <p>Background Circadian disruption (CD) has emerged as a critical factor compromising human health in contemporary society. Increasing evidence suggests that disturbances in circadian rhythms are involved in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease (AD). The hyperphosphorylation of tau and the deposition of amyloid-β (Aβ) are recognized as major patholog...

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Literature Corpus work: a202c5f2-98fc-5fbe-bdd0-ff25e16e2aca
DOI: 10.21203/rs.3.rs-6773012/v1

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