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Article

Circadian disruption induces sex-specific Alzheimer’s pathophysiology and immune cell reprogramming

2026-05-05

Abstract excerpt

<h4>Summary</h4> Circadian disruption (CD) is increasingly recognized as a sex-specific risk factor for Alzheimer’s disease (AD). However, the mechanisms linking CD to AD, and the role of biological sex in this interaction, are unclear. Immunometabolic regulation is extensively circadianly timed, has sex-specific phenotypes, and plays a role in AD. Therefore, we hypothesized that CD affects the timing of immunome...

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Literature Corpus work
51a92c90-cd52-531d-82ad-4ab241622e47
DOI
10.64898/2026.04.30.721994
Open publication

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Circadian disruption induces sex-specific Alzheimer’s pathophysiology and immune cell reprogrammingDOI 10.64898/2026.04.30.721994
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