Article

Evolution of genome and immunogenome in esophageal squamous cell carcinomas driven by neoadjuvant chemoradiotherapy

2024-02-05

Abstract excerpt

<h4>Background: </h4> Neoadjuvant chemoradiotherapy (NCRT) followed by surgery is a standard treatment for locally advanced esophageal squamous cell carcinomas (ESCCs). However, evolution of genome and immunogenome in ESCCs driven by NCRT remain incompletely elucidated. Methods We performed whole-exome sequencing of 51 ESCC tumors collected before and after NCRT, 36 of which were subjected to transcriptome sequen...

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Literature Corpus work: 76ca2ee9-3afe-5da1-ba49-52d22a0644de
DOI: 10.21203/rs.3.rs-3912458/v1

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