Article

Tumor microenvironment distinctions between esophageal cancer subtypes explain varied immunotherapy responses

2024-09-26

Abstract excerpt

Esophageal cancer comprises two main subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC). Previous studies have revealed distinct genomic characteristics between these subtypes, with ESCC sharing similarities with head and neck squamous cell carcinoma (HNSCC), and EAC aligning with gastric adenocarcinoma (GAC). Additionally, recent immunotherapy clinical trials have shown a high...

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Literature Corpus work: 649c763d-5117-5ca7-a525-ad2801f863e5
DOI: 10.1101/2024.09.24.614705

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