Article

A Comprehensive Survey of Mutations in Oesophageal Carcinoma Reveals Recurrent Neoantigens as Potential Immunotherapy Targets

2020-03-30

Abstract excerpt

This study was aimed to investigate the mutations in Esophageal Carcinoma (EC) for recurrent neoantigen identification. A total of 733 samples with whole exome sequencing (WES) mutation data and 1153 samples with target region sequencing data were obtained from 7 published studies and GENIE database. Common HLA-I and HLA-II genotypes in both TCGA cohort and Chinese were used to predict the probability of ‘public’...

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Literature Corpus work: 3e3dd9f0-56c6-5c98-acd9-f1e4bcfb7dca
DOI: 10.1101/2020.03.28.013201

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