Article

Tumor Niche Network-Defined Subtypes Predict Immunotherapy Response of Esophageal Squamous Cell Cancer

2023-02-15

Abstract excerpt

<h4>Summary</h4> Despite the promising outcomes of immune checkpoint blockade (ICB), resistance to ICB presents a new challenge. Therefore, selecting patients for specific ICB applications is crucial for maximizing therapeutic efficacy. Herein we curated 69 human esophageal squamous cell cancer (ESCC) patients’ tumor microenvironment (TME) single-cell transcriptomic datasets to subtype ESCC. Integrative analyses...

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Literature Corpus work: 2f329aea-ea6d-5d30-8a9b-7bba6d867da8
DOI: 10.1101/2023.02.15.528539

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