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Construction of <i>lux</i> -based promoter-reporter platforms in <i>Mycobacterium bovis</i> BCG for screening of drug repurposing small-molecule compounds as new anti-tuberculosis drugs

2021-11-06

Abstract excerpt

The emergence of multidrug-resistant strains and hyper-virulent strains of Mycobacterium tuberculosis are big therapeutic challenges for tuberculosis (TB) control. Repurposing bioactive small-molecule compounds has recently become a new therapeutic approach against TB. This study aimed to construct a rapid screening system to identify novel anti-TB agents from a library of small-molecule compounds. In this study...

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Literature Corpus work
75e78f85-0392-562a-88ee-52c9b05f33f7
DOI
10.1101/2021.11.05.467536
Open publication

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Construction of <i>lux</i> -based promoter-reporter platforms in <i>Mycobacterium bovis</i> BCG for screening of drug repurposing small-molecule compounds as new anti-tuberculosis drugsDOI 10.1101/2021.11.05.467536
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